New Hair Loss Treament 2014
Update: February 2014
Cloning Hair for Hair Loss Update
G’Day from Australia’s National Hair Institute – My name is Scott Moore and I am the General Manager for the National Hair Institute in Melbourne and the Dr Hair Hair Loss Clinic in Sydney. On behalf of Dr Barry White, Dr Bee Kho & all of my Hair Loss + Hair Transplant Experts that work with us at Dr Hair & the NHI, thanks for taking time to read this blog regarding New Hair Loss Loss Treatments.
New Hair Loss Treatment Update #15
This edition of New Hair Loss Treatments was published in February 2014. The information enclosed below is made available to help men and women suffering with hair loss to be able to keep informed on the progress in the medical world to treat varying forms of hair loss. This article, the contents on the website & the contents in any quoted website/link do not constitute as any of recommendation. Only after completing a full Hair Loss Assessment & Review by a member of our staff are we able to provide any recommendation or consideration.
New Hair Loss Treatment Topics reviewed in Feb 2014 Include:
- Platelet Rich Plasma also known as PRP for Hair Loss
- Hair Cloning & Hair Follicle Cloning
Hair Cloning & Hair Follicle Cloning
Hair Cloning and follicle multiplication are common subjects that clients ask us regularly when we have our hair loss & hair treatment consultation. The ISHRS.org (International Society of Hair Restoration Surgeons) holds regular conferences for the doctors specialising in hair restoration, hair transplantation and preventative hair loss treatments. These conferences are a great opportunity for leading surgeons and medical experts to converge and collaborate on the various learnings they have attained in the treatment of male pattern hair loss and female hair loss also known as Androgenetic Alopecia. At the 2012 conference, the agenda published via this hair loss update on the ISHRS.org website listed the following hair loss treatment discussions/subjects;
- Bioenhancements of hair restoration surgery, such as the use of platelet rich plasma (PRP for Hair) harvested from the patient’s own blood and a bioengineered cellular matrix
- Advances in techniques to induce hair growth:
- Environmental influences on regeneration techniques
- Possible hair follicle regeneration and cloning updates
- Scalp injections to induce hair regrowth
- Application of automation and robotics to hair restoration surgery
Platelet Rich Plasma
Platelet Rich Plasma aka PRP is a medical procedure that seeks to harvest the growth factors naturally found in a persons blood and apply these to minaturising hair follicles to rejuvenate and regenerate the growth of hair. Specifically, PRP for hair loss is currently not FDA approved in the treatment of androgenetic alopecia. And this has caused a large amount of noise amongst hair transplantation and hair loss treatment medical centres. The ISHRS.org have for many years provided grants to various Doctors and Surgeons to further research and develop techniques that are innovative hair transplant and hair loss treatment options – Platelet Rich Plasma for Hair has featured heavily in the funding allocation since 2009. The International Society of Hair Restoration Surgeons provide further reading on PRP and this can be read by clicking here. At the National Hair Institute of Australia, a high level overview of hair loss and how PRP for hair can help treat male and female pattern hair loss is below:
1. Minaturisation of the hair follicle results because of the inheritance of the “balding gene” & the presence of a hormone known as DHT (the hair loss hormone). The combination of these 2 elements causes the hair follicle to minaturise and move closer to the surface of the skin, and away from its blood supply. This results in a reduction in the supply of blood to the hair follicle.
2. The hair follicle requires this blood supply in order to be able to grow a thick and full hair.
3. PRP Platelet Rich Plasma requires a doctor to harvest a sample of blood from a patient, and isolate the growth factors found naturally within that 10-20mL blood sample; these growth factors can be found in the plasma and platelets of the blood and these are isolated after the centrifuge process.
4. Once prepared and sourced, the PRP is then injected into the scalp where a patient is thinning, is planning to have a transplant, is having scar revision or preparing the donor hair for the transplant. It acts in the capacity of a fertiliser and stimulates the follicle to regrow a thicker and healthier hair, or the skin to build up its rejuvenation abilities in the lead up to a hair transplant.
Since 2012, more than 800 Platelet Rich Plasma for hair treatments have been performed by Dr Barry White from the National Hair Institute and Dr Bee Kho of Dr Hair Sydney. Our review of the results include:
1. The younger the PRP patient, the quicker and fuller the result following 3 x Initial PRP for Hair Loss Treatments, where the hair loss is in its early stages.
2. The approach of using a mechanical implement (ie needle gun) can result in a loss in the amount of serum that penetrates the skin – this is why this approach is not adopted by the NHI.
3. Patients 50+ years of age have benefited from the treatment, they feel that the hair is stronger and grows more upright, rather than being flat and lifeless. These patients do see an improvement, however the improvement is not as significant as the results achieved by a patient who is under the age of 30yrs. It is still worth re-confirming, that all patients are reporting benefits after 9-12mths of PRP for hair loss therapy.
4. Where the thinning hair is heavily minaturised, this hair is unlikely to be visibly improved, however over a 12 month period, the volume of shedding has decreased noticeably.
5. Patients who do PRP in the lead up to their hair transplant procedure experience less temporary shock loss & a faster recovery post hair transplant procedure.
6. Patients who a high rate of minaturisation (hair thinning) who rely on PRP notice the rate of shedding increase in the first month, then decrease. Including minoxidil into the process shows the initial shedding phase increase further, then decrease further again, compared with those only using PRP.
7. Patients who combined finasteride (without experiencing any side effects) felt their hair loss had stabilised and slowed down the rate of loss / shedding than when they were previously only consuming finasteride.
*It must be clearly stated that this information has been provided by patients and have not been validated using any clinical assessment. ~94% of patients who did PRP for Hair at the NHI for the initial 12mths, renewed their hair loss treatment plan for the 2nd year. Further validating that although PRP is not an FDA approved treatment for Androgenetic Alopecia, the National Hair Institute’s patients are happy with the outcome it is achieving for them and their hair restoration goals / aspirations. The patient reviews were not completed in a clinic testing environment.
The National Hair Institute & Dr Hair are always on the lookout for ways to increase the performance of PRP Platelet Rich Plasma by reviewing complimentary therapies such as scalp cleansing, skin needling, topical serums, vitamin boosts and blood enriching & detoxifying preparation treatments. For the best PRP for Hair treatment, a wholistic and balanced approach needs to be taken. This is our goal at the National Hair Institute in Melbourne and Dr Hair in Sydney.
Cloning & Hair Transplants
For many years now, the hair loss world has been buzzing around the concept of cloning human hair follicles for hair replacement and transplant purposes, however successfully cloning human hair follicle has proved very challenging. For more than 40 years scientists have been attempting to achieve a break through have been successfully able to generate new follicle growth in tests.
“…Specialised cells called the dermal papillae can be induced to form hair follicles in laboratory rats but the same process has evaded scientists working on human dermal papillae for 40 years, said Professor Colin Jahoda of Durham University, the co-leader of the study.
Human dermal papilla cells do not respond in the same way as rat cells when grown in conventional, flat culture dishes. But when they are grown in three-dimensional “spheroids” – drops hanging down from a glass slide – they can be re-programmed into dermal papillae that can trigger the formation of hair follicles when transplanted into human skin grown on the backs of mice, Professor Jahoda said.
Seven patients donated skin cells for the research and in five cases the resulting hair follicles caused the regrowth of human hair on the back of the experimental mice which lasted for at least six weeks, he said. ……”It could make hair transplantation available to individuals with a limited number of follicles, including those with female-pattern hair loss, scarring alopecia and hair loss due to burns,” Professor Jahoda said.”
The full article is available here. http://www.independent.co.uk/news/science/radical-new-therapy-to-tackle-baldness-is-just-a-hairs-breadth-away-after-discovery-8894760.html
Another article on the matter can be found at the online publication, Medical News Today at the following post; http://www.medicalnewstoday.com/articles/267732.php
The Medical News Today article explains:
“…The idea of cloning hair follicles has been around for decades. Scientists already know that dermal papilla cells, that are found inside the hair follicles, can give rise to new follicles…However, once the dermal papilla cells are put into conventional, two-dimensional tissue culture, they revert to basic skin cells and lose their ability to produce hair follicles. So we were faced with a catch-22: how to expand a sufficiently large number of cells for hair regeneration while retaining their inductive properties….They found their way out of the catch-22 when they observed how hair grows on mice and other rodents. Prof. Jahoda, one of the early founders of stem cell sciences, has been working on methods of harvesting, expanding and successfully transplanting rodent skin cells back into their skin for years.”
Colin Jahoda, Professor of stem cell sciences at Durham and co-director of North East England Stem Cell Institute with the reporter from the online publication Medical News Today.
There is hope that further clinical studies will move towards new hair loss treatments in 2014 where new hair follicles can be established. Sadly, the hope that 2014 will be the year a breakthrough hair loss treatment will come about is unlikely. However, what we can do is maximise and capitalise on the knowledge and experience that National Hair Institute in Melbourne and Dr Hair Sydney can offer. As until then, there is still only 1 proven way to grow more hair where you are no longer growing it, and that is with a hair transplant procedure. The ultimate way to achieve a fuller head of hair is to combine PRP with Hair Transplantation.
Current Hair Loss Treatments in 2014 consist of:
- FUT Hair Transplantation
- FUE Hair Transplantation
- Platelet Rich Plasma for Hair
- Scalp Health Management Plans
To see which hair loss treatment for you, complete the Dr Hair Sydney & National Hair Institute Melbourne’s Online Hair Loss Questionaire, and we will call you back to discuss your hair loss options in detail.